Probiotical プロバイオティカル - 多様な生菌剤の世界的メーカー
プロバイオティカル社の多様な菌株と領域別菌株
BIFIDOBACTERIUM STRAINS ビフィズス菌株 |
消化器系 | 骨と髪の健康 | 神経系 | |
LACTOBACILLUS STRAINS 乳酸菌株 |
免疫と アレルギー |
心血管代謝 | アイケア | |
STREPTOCOCCUS THERMOPHILUS 連鎖球菌サーモフィルス |
皮膚系 | 婦人系 | スポーツ | |
BLENDS ブレンド |
健康な老化 | 泌尿器系 | オーラルケア |
泌尿器系 |
尿路感染(UTI)
Lactiplantibacillus plantarum LP01™ (LMG P-21021)
(旧名 Lactobacillus plantarum )
Lacticaseibacillus paracasei LPC09 (DSM 24243)
(旧名 Lactobacillus paracasei )
Streptococcus thermophilus ST10 (DSM 25246)
BIFICIST®
機能性
- 膀胱炎
- シュウ酸塩の代謝、腎臓結石の予防
- 大腸菌の抑制
学術サポート
ヒト臨床試験
- Vicariotto F. Effectiveness of An Association of a Cranberry Dry Extract, D-Mannose, and the 2 Microorganisms Lactobacillus plantarum LP01 and Lactobacillus paracasei LPC09 in Women Affected by Cystitis. Journal of Clin Gastroenterol 2014;48:S96-S101.
- Mogna L. et al. Assessment of the in vitro inhibitory activity of specific probiotic bacteria against different Escherichia coli strains. J Clin Gastroenterol. 2012; 46 Suppl:S29-32.
- Mogna L. et al. Screening of different probiotic strains for their in vitro ability to metabolise oxalates: any prospective use in humans? J Clin Gastroenterol. 2014; 48 Suppl:S91-95.
- Deidda F, et al. How Probiotics may Kill Harmful Bacteria: The in vitro Activity against Some Haemolytic Strains. J Prob Health, 2020. Vol. 8 Iss.2 No: 216.
- Amoruso A. et al. (2019) A Systematic Evaluation of the Immunomodulatory and Functional Properties of Probiotic Bifidobacterium Breve BR03 (DSM 16604) Lactobacillus plantarum LP01 (LMG P-21021). J Prob Health. 7:214.
Lactiplantibacillus plantarum LP01™ (LMG P-21021)
(旧名 Lactobacillus plantarum )
Lactiplantibacillus plantarum LP02 (LMG P-21020)
(旧名 Lactobacillus plantarum )
Lacticaseibacillus rhamnosus LR04 (DSM 16605)
(旧名 Lactobacillus rhamnosus )
Lacticaseibacillus rhamnosus LR06 (DSM 21981)
(旧名 Lactobacillus rhamnosus )
Lactiplantibacillus pentosus LPS01 (DSM 21980)
(旧名 Lactobacillus pentosus )
Bifidobacterium breve BR03™ (DSM 16604)
機能性
- 膀胱炎
- 大腸菌、フェカリス菌、肺炎桿菌の抑制
1) LP01 2.5 billion cells + LPC09 1 billion cells + ST10 1 billion cells + tara gum + cranberry extract + D-mannose
*("CFU"は非処理の菌数、"cell"はマイクロカプセル化菌数)
可能形態 単体原体、ブレンド原体、あるいは製剤
学術サポート
インビトロ研究
- Mogna L. et al. Assessment of the in vitro inhibitory activity of specific probiotic bacteria against different Escherichia coli strains. J Clin Gastroenterol. 2012; 46 Suppl:S29-32.
- Deidda F, et al. How Probiotics may Kill Harmful Bacteria: The in vitro Activity against Some Haemolytic Strains. J Prob Health, 2020. Vol. 8 Iss.2 No: 216.
- Amoruso A. et al. (2019) A Systematic Evaluation of the Immunomodulatory and Functional Properties of Probiotic Bifidobacterium Breve BR03 (DSM 16604) Lactobacillus plantarum LP01 (LMG P-21021). J Prob Health. 7:214.
- Nicola S. et al. Interaction between probiotics and human immune cells: the prospective anti-inflammatory activity of Bifidobacterium breve BR03. AgroFOOD, 2010; 21(2):S44-47.
Lactobacillus delbrueckii subsp. delbrueckii LDD01 (DSM 22106)
機能性
- 病原体となる大腸菌、クレブシエラ菌およびガス発生性大腸菌群の抑制
学術サポート
インビトロ研究
- Mogna L. et al. Assessment of the in vitro inhibitory activity of specific probiotic bacteria against different Escherichia coli strains. J Clin Gastroenterol. 2012; 46 Suppl:S29-32.
- Savino F. et al. Antagonistic effect of Lactobacillus strains against gasproducing coliforms isolated from colicky infants. BMC Microbiology 2011, 11:157.
- Mogna L. et al. In Vitro Inhibition of Klebsiella pneumoniae by Lactobacillus delbrueckii subsp. delbrueckii LDD01 (DSM 22106): An Innovative Strategy to Possibly Counteract Such Infections in Humans? J Clin Gastroenterol. 2016 Nov/Dec;50 Suppl 2, Proceedings from the 8th Probiotics, Prebiotics & New Foods for Microbiota and Human Health meeting held in Rome, Italy on September 13-15, 2015:S136-S139.
Bifidobacterium breve B632™(DSM 24706)
機能性
- 病原体となる大腸菌、および腸内細菌科の抑制
学術サポート
インビトロ研究
- Mogna L. et al. Assessment of the in vitro inhibitory activity of specific probiotic bacteria against different Escherichia coli strains. J Clin Gastroenterol. 2012; 46 Suppl:S29-32.
- Simone M. et al. The Probiotic Bifidobacterium breve B632 Inhibited the Growth of Enterobacteriaceae within Colicky Infant Microbiota Cultures. BioMed Research International 1-6, 2014.
Ligilactobacillus salivarius CRL1328 (DSM 24441)
(旧名 Lactobacillus salivarius )
機能性
- 泌尿生殖器感染症の予防
- カンジダの抑制
- 淋病
- エンテロコッカス・フェカリス、エンテロコッカス・フェシウムおよびナイセリア菌の阻害
学術サポート
インビトロ研究
- Ocana V. et al. Characterization of a bacteriocin like substance produced by a vaginal Lactobacillus salivarius strain. Applied and Environmental Microbiology, 1999; 65(12):5631-5635.
- Ocana V. et al. Surface characteristics of Lactobacilli isolated from human vagina. J. Gen. Appl. Microbiol., 1999; 45:203-212.
- Tomas MSJ. et al. Influence of pH, temperature and culture media on the growth and bacteriocin production by vaginal Lactobacillus salivarius CRL 1328. Journal of Applied Microbiology, 2002; 93: 714-724.
- Rovere F. Local tolerability and activity study in patients suffering from Candida albicans (Delmati2 Hospital, Italy, 1992).
- Gillor O. et al. The dual role of bacteriocins as anti- and probiotics. Appl Microbiol Biotechnol. 2008 December; 81(4): 591–606. doi: 10.1007/ s00253-008-1726-5.
- Dover S.E. et al. Natural antimicrobials and their role in vaginal health: a short review. Int J Probiotics Prebiotics. 2008 ; 3(4): 219–230.
- Juárez Tomás M.S. et al. Viability of vaginal probiotic Lactobacilli during refrigerated and frozen storage. Anaerobe, Vol 10, Issue 1, February 2004, 1-5.
前立腺の健康
Lactiplantibacillus plantarum LP01™ (LMG P-21021)
(旧名 Lactobacillus plantarum )
Lacticaseibacillus paracasei LPC09 (DSM 24243)
(旧名 Lactobacillus paracasei )
BIFIPROST®
機能性
- 慢性細菌性前立腺炎の予防
- シュウ酸塩の代謝、腎臓結石の予防
- 抗炎症作用
- 大腸菌の抑制
- 尿路感染症
学術サポート
ヒト臨床試験
- Chiancone F. et al. The Use of a Combination of Vaccinium Macracarpon, Lycium barbarum L. and Probiotics (Bifiprost®) for the Prevention of Chronic Bacterial Prostatitis: A Double-Blind Randomized Study. Urologia Internationalis 2019.
- Mogna L. et al. Assessment of the in vitro inhibitory activity of specific probiotic bacteria against different Escherichia coli strains. J Clin Gastroenterol. 2012; 46 Suppl:S29-32.
- Deidda F, et al. How Probiotics may Kill Harmful Bacteria: The in vitro Activity against Some Haemolytic Strains. J Prob Health, 2020. Vol. 8 Iss.2 No: 216.
- Mogna L. et al. Screening of different probiotic strains for their in vitro ability to metabolise oxalates: any prospective use in humans? J Clin Gastroenterol. 2014; 48 Suppl:S91-95.
- Amoruso A. et al. (2019) A Systematic Evaluation of the Immunomodulatory and Functional Properties of Probiotic Bifidobacterium Breve BR03 (DSM 16604) Lactobacillus plantarum LP01 (LMG P-21021). J Prob Health. 7:214. Internal data on anti-inflammatory and anti-oxidant properties avai-lable upon request.
Bifidobacterium animalis subsp. lactis Bb1 (DSM 17850)
Limosilactobacillus reuteri Lb26 (DSM 16341)
(旧名 Lactobacillus reuteri )
機能性
- 高いバイオアヴェイラビリティのアレルゲンフリーのプロバイオティック株由来の有機亜鉛とセレン
- 正常な認知機能
- 正常な骨の維持
- DNA、タンパク質、脂質を酸化損傷から保護
- 正常なDNA合成と細胞分裂
- 免疫系の正常な機能
学術サポート
インビトロ研究
- Mogna L. et al. Selenium and zinc internalized by Lactobacillus buchneri Lb26 (DSM 16341) and Bifidobacterium lactis Bb1 (DSM 17850): improved bioavailability using a new biological approach. J Clin Gastroenterol. 2012; 46 Suppl:S41-5.
- Mangiapane E. et al. An integrated proteomic and physiological approach to understand the adhesion mechanism of the probiotic Lactobacillus reuteri Lb26 DSM16341. Journal of integrated Omics, 2013.
- Galano E. et al. Privileged Incorporation of Selenium as Selenocysteine in Lactobacillus reuteri Proteins Demonstrated by Selenium-specific Imaging and Proteomics. Molecular & Cellular Proteomics 12.8, 2013.
- Mangiapane E. et al. Selenium effects on the metabolism of a Semetabolizing Lactobacillus reuteri: analysis of envelope-enriched and extracellular proteomes. The Royal Society of Chemistry, 2014.
- Mangiapane E. et al. Selenium and Selenoproteins: An Overview on Different Biological Systems. Current Protein and Peptide Science, 2014, 15, 598-607.
腎臓結石
Lacticaseibacillus paracasei LPC09 (DSM 24243)
(旧名 Lactobacillus paracasei )
可能形態 ブレンド原体、あるいは製剤
Lactobacillus acidophilus LA02 (DSM 21717)
Lactiplantibacillus plantarum LP01™ (LMG P-21021)
(旧名 Lactobacillus plantarum )
Limosilactobacillus reuteri LRE02 (DSM 23878)
(旧名 Lactobacillus reuteri )
Bifidobacterium animalis subsp. lactis Bb1 (DSM 17850)
Bifidobacterium breve BR03™ (DSM 16604)
Bifidobacterium longum BL03 (DSM 16603)
可能形態 単体原体、ブレンド原体、あるいは製剤
機能性
- シュウ酸分解
- 腎臓結石の発生率が減少する可能性
- 腸の炎症の軽減
学術サポート
インビトロ研究
- Mogna L. et al. Screening of different probiotic strains for their in vitro ability to metabolise oxalates: any prospective use in humans? (LPC09, LA02, LP01, LRE02, BR03, BL03) J Clin Gastroenterol. 2014; 48 Suppl:S91-95.
- Deidda F, et al. How Probiotics may Kill Harmful Bacteria: The in vitro Activity against Some Haemolytic Strains. J Prob Health, 2020. Vol. 8 Iss.2 No: 216.
- Amoruso A. et al. (2019) A Systematic Evaluation of the Immunomodulatory and Functional Properties of Probiotic Bifidobacterium Breve BR03 (DSM 16604) Lactobacillus plantarum LP01 (LMG P-21021). J Prob Health. 7:214.
- Nicola S. et al. Interaction between probiotics and human immune cells: the prospective anti-inflammatory activity of Bifidobacterium breve BR03. AgroFOOD, 2010; 21(2):S44-47.
- Mogna L. et al. Assessment of the in vitro inhibitory activity of specific probiotic bacteria against different Escherichia coli strains. J Clin Gastroenterol. 2012; 46 Suppl:S29-32.